- A Case of Superior Orbital Fissure Syndrome Attributed to Sinusitis Presenting Unilateral Throbbing Headache
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Byung-Su Kim, Byung-Kun Kim, Soo-Kyoung Kim, Jae-Moon Kim, Heui-Soo Moon, Kwang-Yeol Park, Jong-Hee Sohn, Tae-Jin Song, Min Kyung Chu, Myoung-Jin Cha, Soo-Jin Cho, J
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Published online December 31, 2017
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- 두통 초진 환자에서 이차두통의 임상적 예측인자: 다기관 연구
- The Frequency and Characteristics of Other Primary Headache Disorders in First-Visit Headache Patients in Korea: A Multicenter Study
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Myoung-Jin Cha, Byung-Kun Kim, Byung-Su Kim, Jong-Hee Sohn, Soo-Kyoung Kim, Heui-Soo Moon, Tae-Jin Song, Jae-Moon Kim, Jeong Wook Park, Min Kyung Chu, Kwang-Yeol Park
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Published online December 31, 2017
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- 신경과 외래를 방문한 두통 초진 환자에서 기타 원발두통의 빈도와 특징 - 다기관 연구
- Aggravation by Routine Physical Activity and Associated Factors in the Korean Migraine Population
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Byung-Su Kim, Min Kyung Chu, Byung-Kun Kim, Jae-Moon Kim
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Published online June 30, 2015
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- 한국인 편두통 인구에서 일상신체활동에 의한 두통의 악화와 관련 인자
- Therapeutic Strategies in Patients with Spontaneous Intracranial Hypotension or Post-dural
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Juyoun Lee, Sungbo Kim, Ji-Eun Oh, Jae-Moon Kim
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Published online June 30, 2014
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- 자발두개내압저하와 경막천자후두통 환자에서의 치료에 대한 후향적 연구
- 만성편두통에서 돌외추출물의 효과와 안정성: 무작위, 이중맹검, 위약대조법을 이용한 연구
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Seong-Hae Jeong, Jae-Moon Kim, Mi Sook Park, Myung Koo Lee
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Korean J Headache. 2012;13(1):1-6. Published online June 30, 2012
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- Objective: To evaluate the clinical efficacy and safety of a standardized special ethanol extract from Gynostemma pentaphyllum (GP-EX) as a management of chronic migraine.
Methods
This is a two-arm, parallel-group, randomized trial comparing GP-EX 20 mg bid or placebo bid in 64 patients with chronic migraine. Eligible patients were those who meet the broader concept of chronic migraine. The main outcome measure was the decrease in visual analogue scale (VAS) of general pain including headache and anxiety scale from baseline over a 6 weeks treatment period.
Results
The VAS decreased from 4.6±2.3 before treatment to 2.8±2.6 after 6 week of GP-EX treatment (vs. placebo: from 5.4±1.9 to 3.9±2.8 p=0.017). In all questionnaires using in this study, the anxiety in group with GP-EX was decreased significantly than one in patients with placebo (STAI-S=from 47.6±10.8 (mean±SD) to 43.7±10.7 in patient with GP-EX, p=0.017 vs. from 48.3±12.9 to 45.8±10.2 in patients with placebo, p>0.05; STAI-T=from 48.8±11.5 to 43.2±11.6 in patient with GP-EX, p=0.017 vs. from 48.4±11.2 to 44.8±11.5 in patients with placebo, p>0.05; ASI =from 32.4±14.3 to 26.3±16.2 in patient with GP-EX, p=0.017 vs. from 30.2±14.2 to 25.4±13.8 in patients with placebo, p>0.05). The most frequent adverse reactions considered possibly related to treatment were mild gastrointestinal events.
Conclusions
GP-EX 20 mg bid treatment might be effective in reducing general pain and anxiety in chronic migraine patients.
- 두통의 진단과 분류
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Jae-Moon Kim
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Korean J Headache. 2009;10(1):1-13. Published online June 30, 2009
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- Most of headache is primary headache and optimal diagnosis needs proper and time consuming history taking. Information attained by thorough history taking and additional physical and neurological examination should be fit to the diagnostic criteria of each headache disorders. Laboratory tests or imaging studies are usually necessary in the patients with atypical symptoms or neurologic abnormalities, and intractable or progressive headache in spite of optimal treatment. After the long debate of headache classification, currently using IHS(international headache society) classification made correct diagnosis and sharing information possible in the field of headache. As headache is one of the common illnesses that significantly impair quality of life in human, even primary physician should be acquainted with this classification and diagnostic criteria.
- Migrainous Brain: Is It Different from Normal Brain?
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Eung Seok Oh, Jae-Moon Kim
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Published online December 31, 2008
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- 편두통 환자의 뇌는 정상과 다른가?
- 자가편두통 선별 도구의 개발 및 타당도 평가 -한국 편두통 선별 설문-
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Min-Kyung Chu, Byung Kun Kim, Sung Taek Kim, Jae-Moon Kim, Heui-Soo Moon, Jeong Wook Park, Kwang-Soo Lee, Kyung-Mi Oh, Jae-Myun Chung, Chin-Sang Chunge
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Korean J Headache. 2007;8(2):84-91. Published online December 31, 2007
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- Background
Migraine is a common and disabling illness. But substantial migraine sufferers were underdiagnosed or undiagnosed. To improve migraine diagnosis, Korean Migraine Screening Questionnaire(KMSQ) was developed and validated in outpatient setting. Methods: A total of 507 patients who visited out patient clinic for headache were recruited in 10 hospitals in Korea and asked 10-item questionnaire concerning headache. 487 completed and returned the questionnaire. All patients were evaluated for headache and diagnosed by headache experts. Migraine diagnosis was assigned on International Head- ache Society(IHS) criteria after completing semi-structured diagnostic interview. Results: Of ten diagnostic questions derived from IHS criteria and headache expert experience, three-item subsets were deduced. Combination of questions regarding nausea, pulsating quality and photophobia showed optimum perfor- mances. Any two from the three items showed a sensitivity of 0.74, a specificity of 0.80, a positive predictive value of 80.8 and a negative predictive value of 73.5. Conclusion: The three-item Korean Migraine Screening Questionnaire was a valid and reliable migraine screening instru- ment in outpatient setting. It could help in improvement of migraine diagnosis and enhance migraine management.
- 증례 : 자발성 접형동 후벽 누관에 의한 세균성 뇌막염 1례
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Jun-Young Lee, Dae-Hyun Kim, Jae-Moon Kim
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Korean J Headache. 2006;7(2):115-117. Published online December 31, 2006
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- Spontaneous cerebrospinal fluid(CSF) fistula constitutes only 3% to 4% of all CSF fistulas. The posterior wall of sphenoid sinus is rarely implicated as a site of spontaneous CSF fistula. A 41-year-old woman was admitted for headache, fever and continuous rhinorrhea. She had not experienced head injury. The CT scan revealed the pneumocephalus and a defect at the posterior part of sphenoid sinus. Bacterial meningitis was diagnosed by the CSF examination. The rhinorrhea was found to have a glucose content compatible with CSF. By isovist CT cisternography, we found? CSF fistula was likely to be on the left posterior wall of sphenoid sinus. We performed transnasal endoscopic sinus surgery with anti- biotic treatment. She recovered from her symptoms and has been free of CSF rhinorrhea. Because CSF rhinorrhea and pneumocephalus implicates the bony defect, rapid evaluation and treatment for a CSF leak site is essential.
- 한국에서 편두통 예방 치료를 위한 평가 - 편두통에 의한 장애인식 캠페인 -
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Min-Kyung Chu, Sun Uck Kwon, Manho Kim, Byung-Kun Kim, Byung-Joo Kim, Yeong-In Kim, Yong-Jae Kim, Won-Joo Kim, Jae-Moon Kim, Hyun Sook Kim, Jin Kuk Do, Ki-Jong Park@
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Korean J Headache. 2005;6(2):121-128. Published online December 31, 2005
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- Background
Migraine is a common, disabling illness and imposes great burden on society. Migraine- related disability is often poorly communicated between patients and physicians. The prevalence, disability and medical service utilization behavior of migraine has not been evaluated sufficiently in Korea. The goal of this study is to determine the proportion of migraine among patients presented with headache in neurology clinic and to assess the level of headache related disability of patients.
Methods
This survey recruited patients who consulted to neurologists with a chief complaint of headache in 17 hospitals in Korea. Patients answered a self-administered questionnaire. The investigators independently responded another questionnaire about their patients' headache and assessed headache related disabilities after diagnostic interview. Patients suffering from headache ≥15 days per month were excluded.
Results
Among 570 patients (female 433 (76.0%), mean age 47.8±15.6) who responded adequately the questionnaire, 376 patients had migraine. Fifty-eight percent of the migraine patients were newly diagnosed as having migraine through this survey. However, 74.9% of migraineurs have taken pain-relieving drugs when headache developed; 12.3% of the migraineurs overused the medications. One hundred forty one (37.5%) migraineurs reported that they miss family, social and leisure activities because of headache. Thirty percents of migraineurs were on prophylactic medications and 14.4% of them have visited emergency room due to severe headache. The neurologists would recommend prophylactic medication in 64.3% of patients who were not on prophylaxis.
Conclusions
This study showed that migraine is the most common headache syndrome in the neu- rology clinics of Korea. Significant portion of the migraine patients have migraine-related disability. A majority of migraineurs exposed pain-relieving drugs without exact diagnosis and some of them overused them. Korean Journal of Headache 6(2):121-128, 2005
- 합병증을 동반한 편두통 1례
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Ye-Sung Kim, Ji-Sun Kim, Sung-Hae Jung, Jae-Moon Kim
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Korean J Headache. 2003;4(2):109-112. Published online December 31, 2003
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- A 30-year old woman was admitted to the psychiatric department because of severe headache, right hemiparesis, aphasia, epileptic seizure, and fluctuating confusion. Headache lasts for couple of weeks and slowly regressed. Right hemiparesis, aphasia and fluctuating confusion was continued in spite of anti- migrainous medications. MRI and brain SPECT revealed suspicious focal ischemic lesion in right deep parietal lobe. There might be a profound overlap between the confusional migraine, basilar artry mi- graine, hemiplegic migraine, and migraine-related cerebral ischemia. Korean Journal of Headache 4(2):109-112, 2003
- 편두통 비급성기에서의 대뇌피질 과흥분성
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Jae-Moon Kim
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Korean J Headache. 2000;1(1):49-56. Published online June 30, 2000
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- Pathogenesis of migraine is still far from clear understanding. Vascular, neurogenic and mixed mecha- nisms are suggested as its etiogenesis. Currently, clinical characteristics of paroxysmal attack, common genetic trait, and neurophysiological evidence of hyperexcitability of cortical neuron in migraineurs sugges- ted migraine as an episodic disorder sharing common pathogenesis, certain types of epilepsy, and other channelopathies. Paroxysmal nature of migraine precipitated by trigger factors resembles periodic paralysis or episodic ataxia. Also, though genetic basis of migraine needs to be determined, the classical concept of genetic trait playing a crucial role in migraine attack is well established. Neurophysiological data from migraineurs are controversial in many aspects, but previous investigations using transcranial magnetic stimulation(TMS), visual evoked potentials(VEPs), and other evoked potentials suggests the cortical neurons of migraine patients are more easily excitable and facilitated than controls. Recently, functional MRI(fMRI) showed hyperemia during the classic spreading depression of potassium-induced migraine in rats. Prog- ression in neurophysiological methods and imaging technique will be helpful in understanding the mechanisms of migraine and clinical diagnosis as well. Research for genetic and molecular basis of migraine is largely obtained from uncommon varieties of familial hemiplegic migraine and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy(CADASIL). Although molecular and genetic understanding of migraine headache in these disorders are firmly established, whether these findings can be generalized in classic/common migraine patients is still under investigation. These new concepts of pathogenesis of migraine answers to many old questions of the nature of spreading depression, triggering of migraine attacks, and the precise cellular mechanisms undergoing in the brain of migraine patients. Korean Journal of Headache 1(1):49-56, 2000
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